Structure of PDB 1agf Chain A

Receptor sequence
>1agfA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIFKTNTQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB1agf Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 D9 N63 I66 T69 N70 T73 D74 S77 Y84 S97 Y99 Y123 T143 W147 V152 Q155 D156 Y159 W167 Y171 Y7 D9 N63 I66 T69 N70 T73 D74 S77 Y84 S97 Y99 Y123 T143 W147 V152 Q155 D156 Y159 W167 Y171
External links
PDB RCSB:1agf, PDBe:1agf, PDBj:1agf
PDBsum1agf
PubMed8976183
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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