Structure of PDB 1agd Chain A

Receptor sequence

>1agdA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIFKTNTQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP

3D structure

PDB

1agd Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.

Chain

Resolution

2.05 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Y7 D9 N63 I66 N70 T73 D74 E76 S77 N80 Y84 S97 Y99 Y116 Y123 T143 W147 Q155 D156 Y159 Y171	Y7 D9 N63 I66 N70 T73 D74 E76 S77 N80 Y84 S97 Y99 Y116 Y123 T143 W147 Q155 D156 Y159 Y171

External links

PDB	RCSB:1agd, PDBe:1agd, PDBj:1agd
PDBsum	1agd
PubMed	8976183
UniProt	P01889\|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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