Structure of PDB 1aei Chain A

Receptor sequence
>1aeiA (length=315) Species: 6087 (Hydra vulgaris) [Search protein sequence]
VVQGTVKPHASFNSREDAETLRKAMKGIGTDEKSITHILATRSNAQRQQI
KTDYTTLFGKHLEDELKSELSGNYEAAALALLRKPDEFLAEQLHAAMKGL
GTDENALIDILCTQSNAQIHAIKAAFKLLYKEDLEKEIISETSGNFQRLL
VSMLQGGRKEDEPVNAAHAAEDAAAIYQAGEGQIGTDESRFNAVLATRSY
PQLHQIFHEYSKISNKTILQAIENEFSGDIKNGLLAIVKSVENRFAYFAE
RLHHAMKGLGTSDKTLIRILVSRSEIDLANIKETFQAMYGKSLYEFIADD
CSGDYKDLLLQITGH
3D structure
PDB1aei Crystal structure of the annexin XII hexamer and implications for bilayer insertion.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A K68 L71 E76 K67 L70 E75
BS02 CA A M26 G28 G30 E70 M25 G27 G29 E69
BS03 CA A G181 Q184 I185 G186 E226 G180 Q183 I184 G185 E225
BS04 CA A M257 K258 G259 G261 D301 M256 K257 G258 G260 D300
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:1aei, PDBe:1aei, PDBj:1aei
PDBsum1aei
PubMed7477411
UniProtP26256|ANX12_HYDVU Annexin-B12 (Gene Name=ANXB12)

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