Structure of PDB 1adj Chain A

Receptor sequence
>1adjA (length=420) Species: 274 (Thermus thermophilus) [Search protein sequence]
TARAVRGTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFE
KGVGAATDIVRKEMFTFQDRGGRSLTLRPEGTAAMVRAYLEHGMKVWPQP
VRLWMAGPMFRAERPQKGRYRQFHQVNYEALGSENPILDAEAVVLLYECL
KELGLRRLKVKLSSVGDPEDRARYNAYLREVLSPHREALSEDSKERLEEN
PMRILDSKSERDQALLKELGVRPMLDFLGEEARAHLKEVERHLERLSVPY
ELEPALVRGLDYYVRTAFEVHHEEIGAQSALGGGGRYDGLSELLGGPRVP
GVGFAFGVERVALALEAEGFGLPEEKGPDLYLIPLTEEAVAEAFYLAEAL
RPRLRAEYALAPRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLAT
GEQVRLSREEVPGYLLQALG
3D structure
PDB1adj Crystal structure analysis of the activation of histidine by Thermus thermophilus histidyl-tRNA synthetase.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.21: histidine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HIS A E81 T83 E130 Y263 Y264 Y288 G304 F305 E80 T82 E129 Y262 Y263 Y287 G303 F304
Gene Ontology
Molecular Function
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004821 histidine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006412 translation
GO:0006427 histidyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1adj, PDBe:1adj, PDBj:1adj
PDBsum1adj
PubMed9115984
UniProtP56194|SYH_THET8 Histidine--tRNA ligase (Gene Name=hisS)

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