Structure of PDB 1aay Chain A

Receptor sequence

>1aayA (length=85) Species: 10090 (Mus musculus) [Search protein sequence]

RPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTT
HIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR

3D structure

PDB

1aay Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions.

Chain

Resolution

1.6 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	R103 R114 F116 R118 E121 R124 H125 I128 R142 R146 H149 H153 T156 R170 R174 R180	R1 R12 F14 R16 E19 R22 H23 I26 R40 R44 H47 H51 T54 R68 R72 R78
BS02	dna	A	D120 D148 S175 K179	D18 D46 S73 K77
BS03	ZN	A	C107 C112 H125 H129	C5 C10 H23 H27
BS04	ZN	A	C137 C140 H153 H157	C35 C38 H51 H55
BS05	ZN	A	C165 C168 H181 H185	C63 C66 H79 H83

External links

PDB	RCSB:1aay, PDBe:1aay, PDBj:1aay
PDBsum	1aay
PubMed	8939742
UniProt	P08046\|EGR1_MOUSE Early growth response protein 1 (Gene Name=Egr1)