Structure of PDB 1a77 Chain A

Receptor sequence
>1a77A (length=315) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence]
GVQFGDFIPKNIISFEDLKGKKVAIDGMNALYQFLTSIRLRDGSPLRNRK
GEITSAYNGVFYKTIHLLENDITPIWVFDGEPPKLKEKTRKVRREMKEKA
ELKMKEAIKKEDFEEAAKYAKRVSYLTPKMVENCKYLLSLMGIPYVEAPS
EGEAQASYMAKKGDVWAVVSQDYDALLYGAPRVVRNLTTTKEMPELIELN
EVLEDLRISLDDLIDIAIFMGTDYNPGGVKGIGFKRAYELVRSGVAKDVL
KKEVEYYDEIKRIFKEPKVTDNYSLSLKLPDKEGIIKFLVDENDFNYDRV
KKHVDKLYNLIANKT
3D structure
PDB1a77 The crystal structure of flap endonuclease-1 from Methanococcus jannaschii.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D175 D224 D174 D223
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0017108 5'-flap endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0043137 DNA replication, removal of RNA primer

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Molecular Function
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Biological Process
External links
PDB RCSB:1a77, PDBe:1a77, PDBj:1a77
PDBsum1a77
PubMed9699635
UniProtQ58839|FEN_METJA Flap endonuclease 1 (Gene Name=fen)

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