Structure of PDB 1a6a Chain A

Receptor sequence
>1a6aA (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
HVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASF
EAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNV
LICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL
PSTEDVYDCRVEHWGLDEPLLKHWEF
3D structure
PDB1a6a The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3.
ChainA
Resolution2.75 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q9 F24 A52 S53 F54 G58 N62 N69 I72 Q5 F20 A48 S49 F50 G54 N58 N65 I68
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1a6a, PDBe:1a6a, PDBj:1a6a
PDBsum1a6a
PubMed7477400
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

[Back to BioLiP]