Structure of PDB 1a66 Chain A

Receptor sequence
>1a66A (length=178) Species: 9606 (Homo sapiens) [Search protein sequence]
MKDWQLPSHSGPYELRIEVQPKSHHRARYETEGSRGAVKASAGGHPIVQL
HGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSN
TKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLV
FRVHVPQPSGRTLSLQVASNPIECSQRS
3D structure
PDB1a66 Solution structure of the core NFATC1/DNA complex.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R26 R28 R35 G36 K39 R142 Q176 R26 R28 R35 G36 K39 R142 Q176
BS02 dna A Y29 E32 R127 N128 S129 R142 K143 T145 R177 Y29 E32 R127 N128 S129 R142 K143 T145 R177
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:1a66, PDBe:1a66, PDBj:1a66
PDBsum1a66
PubMed9506523
UniProtO95644|NFAC1_HUMAN Nuclear factor of activated T-cells, cytoplasmic 1 (Gene Name=NFATC1)

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