Structure of PDB 1a5t Chain A

Receptor sequence
>1a5tA (length=324) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLC
QQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNTLGVDAVREVTEKL
NEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPER
LLATLRSRCRLHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGA
ALALFQGDNWQARETLCQALAYSVPSGDWYSLLAALNHEQAPARLHWLAT
LLMDALKRVTNVDVPGLVAELANHLSPSRLQAILGDVCHIREQLMSVTGI
NRELLITDLLLRIEHYLQPGVVLP
3D structure
PDB1a5t Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C50 C62 C65 C50 C62 C65
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0009360 DNA polymerase III complex
GO:0030894 replisome
GO:0043846 DNA polymerase III, clamp loader complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:1a5t, PDBe:1a5t, PDBj:1a5t
PDBsum1a5t
PubMed9363942
UniProtP28631|HOLB_ECOLI DNA polymerase III subunit delta' (Gene Name=holB)

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