Structure of PDB 1a1m Chain A

Receptor sequence
>1a1mA (length=278) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRPP
WIEQEGPEYWDRNTQIFKTNTQTYRENLRIALRYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEPHH
3D structure
PDB1a1m Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 Y9 N63 Y74 N77 Y84 R97 Y99 D114 Y123 T143 K146 L156 Y159 W167 Y171 Y7 Y9 N63 Y74 N77 Y84 R97 Y99 D114 Y123 T143 K146 L156 Y159 W167 Y171
External links
PDB RCSB:1a1m, PDBe:1a1m, PDBj:1a1m
PDBsum1a1m
PubMed8624812
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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