Structure of PDB 1a1h Chain A

Receptor sequence

>1a1hA (length=85) Species: 10090 (Mus musculus) [Search protein sequence]

RPYACPVESCDRRFSQSGSLTRHIRIHTGQKPFQCRICMRNFSRSDHLTT
HIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR

3D structure

PDB

1a1h High-resolution structures of variant Zif268-DNA complexes: implications for understanding zinc finger-DNA recognition.

Chain

Resolution

1.6 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	F116 Q118 S121 R124 H125 I128 R142 S145 R146 H149 H153 T156 R174 E177 R180	F14 Q16 S19 R22 H23 I26 R40 S43 R44 H47 H51 T54 R72 E75 R78
BS02	dna	A	S119 D148 S175 K179	S17 D46 S73 K77
BS03	ZN	A	C107 C112 H125 H129	C5 C10 H23 H27
BS04	ZN	A	C137 C140 H153 H157	C35 C38 H51 H55
BS05	ZN	A	C165 C168 H181 H185	C63 C66 H79 H83

External links

PDB	RCSB:1a1h, PDBe:1a1h, PDBj:1a1h
PDBsum	1a1h
PubMed	9562555
UniProt	P08046\|EGR1_MOUSE Early growth response protein 1 (Gene Name=Egr1)