Structure of PDB 1a09 Chain A

Receptor sequence
>1a09A (length=106) Species: 9606 (Homo sapiens) [Search protein sequence]
DSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSD
FDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHR
LTTVCP
3D structure
PDB1a09 Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R158 R178 S180 E181 T182 Y187 C188 K203 H204 Y205 K206 G239 R15 R35 S37 E38 T39 Y44 C45 K60 H61 Y62 K63 G96
External links
PDB RCSB:1a09, PDBe:1a09, PDBj:1a09
PDBsum1a09
PubMed9174343
UniProtP12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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