Structure of PDB 1a08 Chain A

Receptor sequence
>1a08A (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF
DNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRL
TTVCP
3D structure
PDB1a08 Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
ChainA
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R158 R178 S180 C188 K203 H204 Y205 K206 R14 R34 S36 C44 K59 H60 Y61 K62
External links
PDB RCSB:1a08, PDBe:1a08, PDBj:1a08
PDBsum1a08
PubMed9174343
UniProtP12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

[Back to BioLiP]