Structure of PDB 8pmq Chain 9

Receptor sequence
>8pmq9 (length=412) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
KSIFNEPDVDFHLKLNQQLFHIPYELLSKRIKHTQAVINKETKSLHEHTA
ALNQIFEHNDVEHDELALAKITEMIRKVDHIERFLNTQIKSYCQILNRIK
KRLEFFHELKDIKSQNEGTRTKLIQWYQSYTNILIGDYLTRNNPIKYNSE
TKDHWNSGVVFLKQSQLDDLIDYDVLLEANRISTSLLHERNLLPLISWIN
ENKKTLTKKSSILEFQARLQEYIELLKVDNYTDAIVCFQRFLLPFVKSNF
TDLKLASGLLIFFERYLNLLDDQRWSVLNDLFLSDFYSMYGISQNDPLLI
YLSLGISSLKTRDCLHLQLFTLHSLKRKNCPVCSETFKPITQALPFAHHI
QSQLFENPILLPNGNVYDSKKLKKLAKTLKKQNLISLNPGQIMDPVDMKI
FCESDSIKMYPT
3D structure
PDB8pmq Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Chain9
Resolution3.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN 9 C395 C434 C314 C330
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0016567 protein ubiquitination
GO:0043066 negative regulation of apoptotic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045721 negative regulation of gluconeogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0034657 GID complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8pmq, PDBe:8pmq, PDBj:8pmq
PDBsum8pmq
PubMed38113892
UniProtP40492|FYV10_YEAST Protein FYV10 (Gene Name=FYV10)

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