Structure of PDB 7pib Chain 9

Receptor sequence

>7pib9 (length=682) Species: 272634 (Mycoplasmoides pneumoniae M129)

TVDLINFRNFGIMAHIDAGKTTTSERILFHSGRIHKIGETHDGESVMDWM
EQEKERGITITSAATSVSWKNCSLNLIDTPGHVDFTVEVERSLRVLDGAI
AVLDAQMGVEPQTETVWRQASRYEVPRIIFVNKMDKTGANFERSVQSIQQ
RLGVKAVPIQLPIGAENDFNGIIDLIEEKVYFFDGGKEEKAEEKPIPDQF
KDQVKQMRAHLVEEVANFDDQLMADYLEGKEISIADIKRCIRKGVIGCQF
FPVLCGSAFKNKGIKLLLDAVVDFLPSPVDVPQAKAYGEDGNEVLISASD
DAPFVGLAFKVATDPFVGRLTFVRVYSGVLKSGSYVKNVRKNKKERVSRL
VKMHAQNRNEIEEIRAGDICAIIGLKDTTTGETLVDDKIDVQLEAMQFAQ
PVISLAVEPKTKADQEKMSIALSKLAEEDPTFKTFTDPETGQTIIAGMGE
LHLDILVDRMRREFKVEVNVGAPQVSFRETFNKESEVEGKYIKQSGGRGQ
YGHVKIRFEPNKDKGFEFVDKIVGGRIPREYIKPVQAGLENAMASGPLAG
YPMIDIKATLFDGSFHEVDSSEMAFKIAASLALKEAGKVCSPVLLEPIMA
IEVTVPEQYFGDTMGDISSRRGLIEGTEQRDNVQVIKAKVPLKEMFGYAT
DLRSFSQGRGNYVMQFSHYAETPKSVVNEIIA

3D structure

• PDB: 7pib Visualizing translation dynamics at atomic detail inside a bacterial cell.
• Chain: 9
• Resolution: 4.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	9	H18 D20 Q55 K57 Q109 M110 Q115 F262 E610 F613 E628 G629 T630 E631 Q637 K640 R656 S657 Q660 G661	H15 D17 Q52 K54 Q106 M107 Q112 F259 E607 F610 E625 G626 T627 E628 Q634 K637 R653 S654 Q657 G658
BS02	rna	9	D45 F319 R349 R352 V526 G527 G528 E575 M576	D42 F316 R346 R349 V523 G524 G525 E572 M573

Gene Ontology

Molecular Function

• GO:0003746 translation elongation factor activity
• GO:0003924 GTPase activity
• GO:0005525 GTP binding

Biological Process

• GO:0006412 translation
• GO:0006414 translational elongation
• GO:0032790 ribosome disassembly

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:7pib, PDBe:7pib, PDBj:7pib
• PDBsum: 7pib
• PubMed: 36171285
• UniProt: P75544|EFG_MYCPN Elongation factor G (Gene Name=fusA)