Structure of PDB 8rg0 Chain 8

Receptor sequence

>8rg08 (length=317) Species: 9606 (Homo sapiens) [Search protein sequence]

GGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDRLEI
TNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTYYGSF
VTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCK
ALKKANITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLAS
SNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQEN
MQRQSRGEPPLPEEDLSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTA
QNLGKLFMAQALQEYNN

3D structure

PDB

8rg0 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining

Chain

Resolution

3.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	8	Q273 Q276 Y277	Q238 Q241 Y242

External links

PDB	RCSB:8rg0, PDBe:8rg0, PDBj:8rg0
PDBsum	8rg0
PubMed
UniProt	O15372\|EIF3H_HUMAN Eukaryotic translation initiation factor 3 subunit H (Gene Name=EIF3H)

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