Structure of PDB 8cqw Chain 8

Receptor sequence

>8cqw8 (length=120) Species: 5476 (Candida albicans)

ALKVRTSTTFRLPKTLKLTRSPKYQRKSVPHYNRLDAHKIIVAPIATETA
MKKVEDGNTLVFQVDIKSNKHQIKSAVKELYDVDALYVNTLIRPNGTKKA
YIRLTSDYDALDIANRIGYI

3D structure

• PDB: 8cqw Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
• Chain: 8
• Resolution: 3.05 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	8	L24 T30 T31 R33 L34 P35 T37 K39 L40 R42 K45 Y46 R48 T69 T71 K75 N91 K92 H93 Y109 N111 T112 L113 I114 P116 K120 K121 Y123 R125	L2 T8 T9 R11 L12 P13 T15 K17 L18 R20 K23 Y24 R26 T47 T49 K53 N69 K70 H71 Y87 N89 T90 L91 I92 P94 K98 K99 Y101 R103
BS02	rna	8	L24 R27 P35 T37 L38 R42 K49 H53 Y54 N55 R56 K61 I88 H93 Q94	L2 R5 P13 T15 L16 R20 K27 H31 Y32 N33 R34 K39 I66 H71 Q72

External links

• PDB: RCSB:8cqw, PDBe:8cqw, PDBj:8cqw
• PDBsum: 8cqw
• UniProt: A0A8H6F6A1