Structure of PDB 4wr6 Chain 78

Receptor sequence

>4wr678 (length=150) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]

MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRR
FEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELL
VRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA

3D structure

PDB

4wr6 Structural insights into the translational infidelity mechanism.

Chain

Resolution

3.05 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	78	L3 S4 R7 N9 G11 A12 N13 K14 R15 R16 K17 R18 R21 G22 P23 G24 G28 K29 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 P48 R50 F51 E52 G53 G54 R55 S56 M60 R61 L62 P63 K64 R65 G66 M67 G69 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 A150	L3 S4 R7 N9 G11 A12 N13 K14 R15 R16 K17 R18 R21 G22 P23 G24 G28 K29 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 P48 R50 F51 E52 G53 G54 R55 S56 M60 R61 L62 P63 K64 R65 G66 M67 G69 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 A150

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015934	large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:4wr6, PDBe:4wr6, PDBj:4wr6
PDBsum	4wr6
PubMed	26037619
UniProt	Q5SHQ7\|RL15_THET8 Large ribosomal subunit protein uL15 (Gene Name=rplO)

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