Structure of PDB 8qbn Chain 7

Receptor sequence
>8qbn7 (length=387) Species: 9606 (Homo sapiens) [Search protein sequence]
RLSQSDEDVIRLIGQHLNGLGLNQTVDLLMQESGCRLPSVMLPPRRLQTL
LRQAVELQRDRCLYHNTKLDSVSLLIDHVCSRRQFPCYTQQILTEHCNEV
WFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIA
WSPDDNYLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDG
KRFVTGGQRGQFYQCDLDGNLLDSWEGVRVQCLWCLSDGKTVLASDTHQR
IRGYNFEDLTDRNIVQEDHPIMSFTISKNGRLALLNVATQGVHLWDLQDR
VLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAE
LTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWGPAP
3D structure
PDB8qbn Non-canonical substrate targeting by the supramolecular CTLH E3 ligase reveals an WDR26-YPEL5 regulatory module
Chain7
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN 7 C300 H303 H320 C322 C62 H65 H78 C80
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0034657 GID complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8qbn, PDBe:8qbn, PDBj:8qbn
PDBsum8qbn
PubMed38759627
UniProtQ9H7D7|WDR26_HUMAN WD repeat-containing protein 26 (Gene Name=WDR26)

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