Structure of PDB 8q6o Chain 7

Receptor sequence
>8q6o7 (length=275) Species: 8355 (Xenopus laevis) [Search protein sequence]
DYQAEKEKCKTFLQEFYKKNFKYGVQLANIAHREQVALCIDLDDLAEEDP
ELVDAICENTRRYTNLFADAVQELLPQYKEREVVHKDALDVYIEHRLMME
QRYPPELMRRFELYFKAPSSSKARVVRDVKADSIGKLVTVRGIVTRVTEV
KPMMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSRECQTNRSGGRLYLQ
TRGSKFIKFQELKIQEHSDQVPVGNIPRCMSVYVRGENTRLAQPGDHVGI
TGVFLPMLRLLSETYLESHRLVKMN
3D structure
PDB8q6o The structural mechanism of dimeric DONSON in replicative helicase activation.
Chain7
Resolution3.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN 7 C183 C205 C161 C183
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0003697 single-stranded DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0017116 single-stranded DNA helicase activity
GO:0046872 metal ion binding
Biological Process
GO:0000727 double-strand break repair via break-induced replication
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006270 DNA replication initiation
GO:0006271 DNA strand elongation involved in DNA replication
GO:0030174 regulation of DNA-templated DNA replication initiation
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005694 chromosome
GO:0042555 MCM complex
GO:0071162 CMG complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8q6o, PDBe:8q6o, PDBj:8q6o
PDBsum8q6o
PubMed37820732
UniProtQ7ZXB1|MCM7B_XENLA DNA replication licensing factor mcm7-B (Gene Name=mcm7-b)

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