Structure of PDB 7r7c Chain 7

Receptor sequence

>7r7c7 (length=104) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence]

SQARNQLANKPSKTKVKKEQSLARLYGAKDLNIPTLNRAIVPGVKIRRGK
KGKKFIADNDTLTLNRLITTIGDKYDDIAESKLEKARRLEEIRELKRKEI
ERKE

3D structure

PDB

7r7c Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.

Chain

Resolution

3.71 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	7	K51 Q54 R58 Y60 G93 K94 K95 F99	K17 Q20 R24 Y26 G49 K50 K51 F55

Gene Ontology

	Biological Process
GO:0000055	ribosomal large subunit export from nucleus
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0008298	intracellular mRNA localization
GO:0017148	negative regulation of translation
GO:0042254	ribosome biogenesis
GO:0042273	ribosomal large subunit biogenesis
GO:0051028	mRNA transport

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0030687	preribosome, large subunit precursor
GO:0101031	protein folding chaperone complex

External links

PDB	RCSB:7r7c, PDBe:7r7c, PDBj:7r7c
PDBsum	7r7c
PubMed	36482249
UniProt	P43586\|LOC1_YEAST 60S ribosomal subunit assembly/export protein LOC1 (Gene Name=LOC1)