Structure of PDB 5e7k Chain 6E

Receptor sequence

>5e7k6E (length=154) Species: 300852 (Thermus thermophilus HB8)

ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQ
EKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLAL
RWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAY
AHYR

3D structure

• PDB: 5e7k Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
• Chain: 6E
• Resolution: 3.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	6E	A2 R3 R4 R6 A7 R10 N28 K29 I30 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 R94 S98 R102 R114 R115 A116	A1 R2 R3 R5 A6 R9 N27 K28 I29 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 R93 S97 R101 R113 R114 A115
BS02	rna	6E	S77 N84 Q86 R143 M144 A147 N148	S76 N83 Q85 R142 M143 A146 N147

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003723 RNA binding
• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0000028 ribosomal small subunit assembly
• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5e7k, PDBe:5e7k, PDBj:5e7k
• PDBsum: 5e7k
• PubMed: 26791911
• UniProt: P17291|RS7_THET8 Small ribosomal subunit protein uS7 (Gene Name=rpsG)