Structure of PDB 8fni Chain 6

Receptor sequence
>8fni6 (length=453) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
SHLSARNIATEALQMKKLHQERGGNPMLAQQARRVLFATSIAGQNLDARS
VALLLNTAVYFGMESDAKLVRECIDYCLKNDKLITVDVLPIVVTACATLK
SRDAREVIEMQAQKAARNAKFLDAKDVTNIISAFSKTGINHEKLFAFLSR
RVQTLARVGEFEAAHLVILANAFSRLRYRDKFLFGAIARRAMSLRERVTV
NELVPLIVAFSKIGLKDPKLSKRFATKAMEYVDQMNAEQVASMFMAFAYF
GIRYDQLFGVLTNRAVELIDEFNAQYISTTLNAFQRIGINNPELFDNLAE
RALAVVQDHDARDISKTVTALAHFGLKDEELFKRLASHAASIADQFDAMG
LVNTAHAFARTNFLQQDMAVALSERSVYVCRLLDAGETRRLLWALAKFQV
RDPKILTPVFNRCLALHYDFFADPTGSEEIEEIFDFYGPNFCPPLYQLYI
SRG
3D structure
PDB8fni Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Chain6
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 6 R64 K75 E79 R107 K183 K194 H223 I226 N229 R233 R235 N259 E260 K270 Y307 R370 M407 R6 K17 E21 R49 K125 K136 H165 I168 N171 R175 R177 N201 E202 K212 Y249 R312 M349
BS02 rna 6 R208 R215 F240 R247 R150 R157 F182 R189
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
Biological Process
GO:0000963 mitochondrial RNA processing
GO:0006396 RNA processing
GO:0044528 regulation of mitochondrial mRNA stability
GO:0090615 mitochondrial mRNA processing
GO:1900864 mitochondrial RNA modification
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0031019 mitochondrial mRNA editing complex
GO:0035770 ribonucleoprotein granule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fni, PDBe:8fni, PDBj:8fni
PDBsum8fni
PubMed37410820
UniProtQ57ZX7

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