Structure of PDB 8fnf Chain 6

Receptor sequence
>8fnf6 (length=452) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
VSHLSARNIATEALQMKKLHQERGGNPMLAQQARRVLFATSIAGQNLDAR
SVALLLNTAVYFGMESDAKLVRECIDYCLKNDKLITVDVLPIVVTACATL
KSRDAREVIEMQAQKAARNAKFLDAKDVTNIISAFSKTGINHEKLFAFLS
RRVQTLARVGEFEAAHLVILANAFSRLRYRDKFLFGAIARRAMSLRERVT
VNELVPLIVAFSKIGLKDPKLSKRFATKAMEYVDQMNAEQVASMFMAFAY
FGIRYDQLFGVLTNRAVELIDEFNAQYISTTLNAFQRIGINNPELFDNLA
ERALAVVQDHDARDISKTVTALAHFGLKDEELFKRLASHAASIADQFDAM
GLVNTAHAFARTNFLQQDMAVALSERSVYVCRLLDAGETRRLLWALAKFQ
VRDPKILTPVFNRCLALHYDFFADPTGSEEIEEIFDFYGPNFCPPLYQLY
IS
3D structure
PDB8fnf Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Chain6
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 6 R64 K75 R107 K183 K194 H223 R233 K270 K274 E296 Y307 R370 M407 R7 K18 R50 K126 K137 H166 R176 K213 K217 E239 Y250 R313 M350
BS02 rna 6 R208 R247 R151 R190
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
Biological Process
GO:0000963 mitochondrial RNA processing
GO:0006396 RNA processing
GO:0044528 regulation of mitochondrial mRNA stability
GO:0090615 mitochondrial mRNA processing
GO:1900864 mitochondrial RNA modification
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0031019 mitochondrial mRNA editing complex
GO:0035770 ribonucleoprotein granule

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Molecular Function
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Cellular Component
External links
PDB RCSB:8fnf, PDBe:8fnf, PDBj:8fnf
PDBsum8fnf
PubMed37410820
UniProtQ57ZX7

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