Structure of PDB 8fnc Chain 6

Receptor sequence
>8fnc6 (length=452) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
VSHLSARNIATEALQMKKLHQERGGNPMLAQQARRVLFATSIAGQNLDAR
SVALLLNTAVYFGMESDAKLVRECIDYCLKNDKLITVDVLPIVVTACATL
KSRDAREVIEMQAQKAARNAKFLDAKDVTNIISAFSKTGINHEKLFAFLS
RRVQTLARVGEFEAAHLVILANAFSRLRYRDKFLFGAIARRAMSLRERVT
VNELVPLIVAFSKIGLKDPKLSKRFATKAMEYVDQMNAEQVASMFMAFAY
FGIRYDQLFGVLTNRAVELIDEFNAQYISTTLNAFQRIGINNPELFDNLA
ERALAVVQDHDARDISKTVTALAHFGLKDEELFKRLASHAASIADQFDAM
GLVNTAHAFARTNFLQQDMAVALSERSVYVCRLLDAGETRRLLWALAKFQ
VRDPKILTPVFNRCLALHYDFFADPTGSEEIEEIFDFYGPNFCPPLYQLY
IS
3D structure
PDB8fnc Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Chain6
Resolution3.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 6 R64 K75 E79 R107 K183 K194 H223 I226 N229 R233 R235 K270 E296 Y307 R344 R370 R7 K18 E22 R50 K126 K137 H166 I169 N172 R176 R178 K213 E239 Y250 R287 R313
BS02 rna 6 R208 Q211 R215 F240 R247 R151 Q154 R158 F183 R190
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
Biological Process
GO:0000963 mitochondrial RNA processing
GO:0006396 RNA processing
GO:0044528 regulation of mitochondrial mRNA stability
GO:0090615 mitochondrial mRNA processing
GO:1900864 mitochondrial RNA modification
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0031019 mitochondrial mRNA editing complex
GO:0035770 ribonucleoprotein granule

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8fnc, PDBe:8fnc, PDBj:8fnc
PDBsum8fnc
PubMed37410820
UniProtQ57ZX7

[Back to BioLiP]