Structure of PDB 7o4i Chain 6

Receptor sequence
>7o4i6 (length=356) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
ASLVASIVEARKKRTAKKNITPYQRGIIRSLILTLDCSEAMLEKDLRPNR
HAMIIQYAIDFVHEFFDQNPISQMGIIIMRNGLAQLVSQVSGNPQDHIDA
LKSIRKQEPKGNPSLQNALEMARGLLLPVPAHCTREVLIVFGSLSTTDPG
DIHQTIDSLVSEKIRVKVLGLSAQVAICKELCKATNYGDESFYKILLDET
HLKELFNEAVTPLPVNKINKGFTLVKMGFPTRIFEDTPTFCSCHSKLVYG
GYFCPNCHSKVCSLPTVCPCCDLMLILSTHLARSYHHLMPLKTFAEVPTT
EKFRSEDCFSCQSRFPILLTSSRYRCEDCKQEFCVDCDVFIHEILHNCPG
CESKPV
3D structure
PDB7o4i Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Chain6
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN 6 C349 C363 C254 C268
BS02 ZN 6 C403 C406 C437 C440 C308 C311 C334 C337
BS03 ZN 6 C429 C432 C451 C326 C329 C348
BS04 ZN 6 C336 H339 C357 C241 H244 C262
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0006351 DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
Cellular Component
GO:0000112 nucleotide-excision repair factor 3 complex
GO:0000439 transcription factor TFIIH core complex
GO:0005634 nucleus
GO:0005675 transcription factor TFIIH holo complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7o4i, PDBe:7o4i, PDBj:7o4i
PDBsum7o4i
PubMed34133942
UniProtQ04673|SSL1_YEAST General transcription and DNA repair factor IIH subunit SSL1 (Gene Name=SSL1)

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