Structure of PDB 6q8x Chain 6

Receptor sequence
>6q8x6 (length=166) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
REGILFTTLEKLVAWGRSNSLWPATFGLACCAIEMMASTDARNDLARFGS
EVFRASPRQADVMIVAGRLSKKMAPVMRRVWEQMPDPKWVISMGACASSG
GMFNNYAIVQNVDSVVPVDVYVPGCPPRPEALIYAVMQLQKKVRGQAYNE
RGERLPPVAAWKRTRG
3D structure
PDB6q8x Key role of quinone in the mechanism of respiratory complex I.
Chain6
Resolution3.508 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HQK 6 T40 G42 M51 T25 G27 M36
BS02 SF4 6 C45 C46 G82 A110 C111 C140 P141 C30 C31 G67 A95 C96 C125 P126
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0050136 NADH:ubiquinone reductase (non-electrogenic) activity
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0009060 aerobic respiration
GO:0015990 electron transport coupled proton transport
Cellular Component
GO:0005886 plasma membrane

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Cellular Component
External links
PDB RCSB:6q8x, PDBe:6q8x, PDBj:6q8x
PDBsum6q8x
PubMed32811817
UniProtQ56218|NQO6_THET8 NADH-quinone oxidoreductase subunit 6 (Gene Name=nqo6)

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