Structure of PDB 5umd Chain 6

Receptor sequence
>5umd6 (length=98) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
SAGDNINAKLQLVMKSGKYQFGRKSCLKALRTGKGKLVIVSSNCPSIQRS
VIEYYAMLSKCGVHDYHGDNNDLGTACGKLFRISCLVITDVGDSDIIK
3D structure
PDB5umd Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.
Chain6
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 6 F28 G29 R30 K31 S32 P52 S53 L87 F88 I90 S91 F21 G22 R23 K24 S25 P45 S46 L80 F81 I83 S84
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5umd, PDBe:5umd, PDBj:5umd
PDBsum5umd
PubMed28288098
UniProtQ8IJK8

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