Structure of PDB 6qw6 Chain 5O

Receptor sequence
>6qw65O (length=306) Species: 9606 (Homo sapiens) [Search protein sequence]
RCSSLQPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDN
YATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHT
SFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTF
NDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL
SNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIA
AGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRL
YMGEIQ
3D structure
PDB6qw6 Mechanism of 5' splice site transfer for human spliceosome activation.
Chain5O
Resolution2.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 5O K106 R146 K148 R182 K183 K184 K55 R95 K97 R131 K132 K133
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000375 RNA splicing, via transesterification reactions
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005682 U5 snRNP
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0005829 cytosol
GO:0016607 nuclear speck
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071013 catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qw6, PDBe:6qw6, PDBj:6qw6
PDBsum6qw6
PubMed30975767
UniProtQ96DI7|SNR40_HUMAN U5 small nuclear ribonucleoprotein 40 kDa protein (Gene Name=SNRNP40)

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