Structure of PDB 6u0m Chain 5

Receptor sequence
>6u0m5 (length=597) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
NTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNE
DIYKKLSDEPSDIIPLFETAITQVAKRISINSLPTFQLILNSNANQIPLR
DLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNT
GNTVSLPRSCNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNL
TMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNSGVAIRTPYIKILGIQSDV
ETVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLM
GGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKG
SSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAI
HEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQ
TTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSE
ISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTER
PITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAAS
3D structure
PDB6u0m DNA unwinding mechanism of a eukaryotic replicative CMG helicase.
Chain5
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna 5 S452 V453 R455 K506 A507 S359 V360 R362 K413 A414
BS02 ATP 5 E498 R549 I650 R651 E405 R456 I554 R555
BS03 ATP 5 I378 F379 P418 G419 T420 A421 K422 S423 Q424 I285 F286 P325 G326 T327 A328 K329 S330 Q331
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005634 nucleus
GO:0042555 MCM complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6u0m, PDBe:6u0m, PDBj:6u0m
PDBsum6u0m
PubMed
UniProtP29496|MCM5_YEAST Minichromosome maintenance protein 5 (Gene Name=MCM5)

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