Structure of PDB 6esb Chain 5

Receptor sequence
>6esb5 (length=338) Species: 1891762 (Betapolyomavirus hominis) [Search protein sequence]
VPKLLIKGGVEVLEVKTGVDAITEVECFLNPEMGDPDENLRGFSLKLSAE
NDFSSDSPERKMLPCYSTARIPLPNLNEDLTCGNLLMWEAVTVQTEVIGI
TSMLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGDPLEMQGVLMNYRTKY
PDGTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNENTRYFG
TFTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADICGLFTN
SSGTQQWRGLARYFKIRLRKRSVKNPYPISFLLSDLINRRTQRVDGQPMY
GMESQVEEVRVFDGTERLPGDPDMIRYIDKQGQLQTKM
3D structure
PDB6esb The Structure of an Infectious Human Polyomavirus and Its Interactions with Cellular Receptors.
Chain5
Resolution3.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SIA 5 L62 L67 K68 N272 S274 T276 Q278 L40 L45 K46 N250 S252 T254 Q256
BS02 CA 5 S213 E216 S191 E194
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0019062 virion attachment to host cell
GO:0046718 symbiont entry into host cell
GO:0075513 caveolin-mediated endocytosis of virus by host cell
Cellular Component
GO:0019028 viral capsid
GO:0039620 T=7 icosahedral viral capsid
GO:0042025 host cell nucleus

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6esb, PDBe:6esb, PDBj:6esb
PDBsum6esb
PubMed29706532
UniProtP03088|VP1_POVBK Major capsid protein VP1

[Back to BioLiP]