Structure of PDB 8cvm Chain 4

Receptor sequence
>8cvm4 (length=66) Species: 1747 (Cutibacterium acnes) [Search protein sequence]
MKQGIHPDYRETTVVCTCGNTFTTRSTSQSGTLNADVCSKCHPFYTGKQK
ILDAGGRVARFERRYG
3D structure
PDB8cvm Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Chain4
Resolution2.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 4 M1 K2 H6 M1 K2 H6
BS02 ZN 4 C18 V37 C38 C41 C18 V37 C38 C41
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:8cvm, PDBe:8cvm, PDBj:8cvm
PDBsum8cvm
PubMed36864821
UniProtQ6A8B4|RL31_CUTAK Large ribosomal subunit protein bL31 (Gene Name=rpmE)

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