Structure of PDB 6q8o Chain 4

Receptor sequence
>6q8o4 (length=384) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MTLNVGPQHPSTHGVLRLMVTLSGEEVLEVVPHIGYLHTGFEKTMEHRTY
LQNITYTPRMDYLHSFAHDLAYALAVEKLLGAVVPPRAETIRVILNELSR
LASHLVFLGTGLLDLGALTPFFYAFRERETILDLFEWVTGQRFHHNYIRI
GGVKEDLPEEFVPELKKLLEVLPHRIDEYEALFAESPIFYERARGVGVIP
PEVAIDLGLTGGSLRASGVNYDVRKAYPYSGYETYTFDVPLGERGDVFDR
MLVRIREMRESVKIIKQALERLEPGPVRDPNPQITPPPRHLLETSMEAVI
YHFKHYTEGFHPPKGEVYVPTESARGELGYYIVSDGGSMPYRVKVRAPSF
VNLQSLPYACKGEQVPDMVAIIASLDPVMGDVDR
3D structure
PDB6q8o Key role of quinone in the mechanism of respiratory complex I.
Chain4
Resolution3.605 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 7.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HQH 4 Q33 H38 G39 Y87 Q8 H13 G14 Y62
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0048038 quinone binding
GO:0050136 NADH:ubiquinone reductase (non-electrogenic) activity
GO:0051287 NAD binding
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6q8o, PDBe:6q8o, PDBj:6q8o
PDBsum6q8o
PubMed32811817
UniProtQ56220|NQO4_THET8 NADH-quinone oxidoreductase subunit 4 (Gene Name=nqo4)

[Back to BioLiP]