Structure of PDB 6esb Chain 4

Receptor sequence
>6esb4 (length=318) Species: 1891762 (Betapolyomavirus hominis) [Search protein sequence]
PKEPVQVPKLLIKGGVEVLEVKTGVDAITEVECFLNPEMGDPDENLRGFS
LKLSAENDFSSDSPERKMLPCYSTARIPLPNLNEDLTCGNLLMWEAVTVQ
TEVIGITSMLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGDPLEMQGVLM
NYRTKYPDGTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNE
NTRYFGTFTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADI
CGLFTNSSGTQQWRGLARYFKIRLRKRSVKNPYPISFLLSDLINRRTQRV
DGQPMYGMESQVEEVRVF
3D structure
PDB6esb The Structure of an Infectious Human Polyomavirus and Its Interactions with Cellular Receptors.
Chain4
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA 4 L62 L67 K68 N272 S274 T276 Q278 L46 L51 K52 N256 S258 T260 Q262
BS02 CA 4 S213 E216 S197 E200
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0019062 virion attachment to host cell
GO:0046718 symbiont entry into host cell
GO:0075513 caveolin-mediated endocytosis of virus by host cell
Cellular Component
GO:0019028 viral capsid
GO:0039620 T=7 icosahedral viral capsid
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6esb, PDBe:6esb, PDBj:6esb
PDBsum6esb
PubMed29706532
UniProtP03088|VP1_POVBK Major capsid protein VP1

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