Structure of PDB 1kc8 Chain 4

Receptor sequence

>1kc84 (length=92) Species: 2238 (Haloarcula marismortui) [Search protein sequence]

MQMPRRFNTYCPHCNEHQEHEVEKVRSGRQTGMKWIDRQRERNSGIGNDG
KFSKVPGGDKPTKKTDLKYRCGECGKAHLREGWRAGRLEFQE

3D structure

PDB

1kc8 Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit

Chain

Resolution

3.01 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	4	M1 Q2 M3 P4 N8 T9 Y10 H13 N15 E16 H17 V25 S27 G28 R29 Q30 T31 M33 K34 W35 I36 R38 Q39 R42 G45 I46 N48 G50 K51 S53 K54 G58 D59 K60 P61 T62 K63 K64 T65 D66 K68 A77 L79 R80 G82 R84 G86 Q91	M1 Q2 M3 P4 N8 T9 Y10 H13 N15 E16 H17 V25 S27 G28 R29 Q30 T31 M33 K34 W35 I36 R38 Q39 R42 G45 I46 N48 G50 K51 S53 K54 G58 D59 K60 P61 T62 K63 K64 T65 D66 K68 A77 L79 R80 G82 R84 G86 Q91
BS02	MG	4	G45 D49	G45 D49

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003735	structural constituent of ribosome
GO:0008270	zinc ion binding
GO:0019843	rRNA binding
GO:0046872	metal ion binding
GO:0070180	large ribosomal subunit rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:1kc8, PDBe:1kc8, PDBj:1kc8
PDBsum	1kc8
PubMed	12860128
UniProt	P32411\|RL44E_HALMA Large ribosomal subunit protein eL42 (Gene Name=rpl44e)