Structure of PDB 6lqu Chain 3C

Receptor sequence
>6lqu3C (length=225) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
VVIEPHRHAGVYIARGKEDLLVTKNMAPGESVYGEKRISVKVEYRVWNPF
RSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAV
EFSHRPGRELISMAKKRPNIIPIIEDARHPQKYRMLIGMVDCVFADVAQP
DQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREER
IKPLEQLTLEPYERDHCIVVGRYMR
3D structure
PDB6lqu Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Chain3C
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 3C G119 R122 G34 R37
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0008649 rRNA methyltransferase activity
GO:1990259 histone H2AQ104 methyltransferase activity
Biological Process
GO:0000451 rRNA 2'-O-methylation
GO:0000452 snoRNA guided rRNA 2'-O-methylation
GO:0000494 box C/D sno(s)RNA 3'-end processing
GO:0006338 chromatin remodeling
GO:0006356 regulation of transcription by RNA polymerase I
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0031167 rRNA methylation
GO:0032259 methylation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:6lqu, PDBe:6lqu, PDBj:6lqu
PDBsum6lqu
PubMed32943522
UniProtP15646|FBRL_YEAST rRNA 2'-O-methyltransferase fibrillarin (Gene Name=NOP1)

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