Structure of PDB 8ir3 Chain 3

Receptor sequence
>8ir33 (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
LVPENLLKKRKAYQALKATQAKQALLAKKEQKLRFKRLESFLHDSWRQKR
DKVRLRRLEVKPHLPDKHSLAFVVRIERIDGVSLLVQRTIARLRLKKIFS
GVFVKVTPQNLKMLRIVEPYVTWGFPNLKSVRELILKRGQAKVKNKTIPL
TDNTVIEEHLGKFGVICLEDLIHEIAFPGKHFQEISWFLCPFHLSVARHA
TKNRVGFLKEMGTPGYRGERINQLIRQLN
3D structure
PDB8ir3 Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Chain3
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 3 R57 F58 R34 F35
BS02 rna 3 Q39 L44 K47 K48 A223 R224 H225 Q20 L25 K28 K29 A197 R198 H199
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001825 blastocyst formation
Cellular Component
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8ir3, PDBe:8ir3, PDBj:8ir3
PDBsum8ir3
PubMed37491604
UniProtQ6DKI1|RL7L_HUMAN Ribosomal protein uL30-like (Gene Name=RPL7L1)

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