Structure of PDB 2hwe Chain 3

Receptor sequence
>2hwe3 (length=238) Species: 12134 (Human rhinovirus 1A) [Search protein sequence]
GLPVYITPGSGQFMTTDDMQSPCALPWYHPTKEISIPGEVKNLIEMCQVD
TLIPVNNVGNNVGNVSMYTVQLGNQTGMAQKVFSIKVDITSTPLATTLIG
EIASYYTHWTGSLRFSFMFCGTANTTLKLLLAYTPPGIDEPTTRKDAMLG
THVVWDVGLQSTISLVVPWVSASHFRLTADNKYSMAGYITCWYQTNLVVP
PSTPQTADMLCFVSACKDFCLRMARDTDLHIQSGPIEQ
3D structure
PDB2hwe A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
Chain3
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide 3 D18 Q20 S21 C23 P26 W27 D18 Q20 S21 C23 P26 W27
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:2hwe, PDBe:2hwe, PDBj:2hwe
PDBsum2hwe
PubMed8383771
UniProtP23008|POLG_HRV1A Genome polyprotein

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