Structure of PDB 1poy Chain 3

Receptor sequence
>1poy3 (length=323) Species: 562 (Escherichia coli) [Search protein sequence]
NNTLYFYNWTEYVPPGLLEQFTKETGIKVIYSTYESNETMYAKLKTYKDG
AYDLVVPSTYYVDKMRKEGMIQKIDKSKLTNFSNLDPDMLNKPFDPNNDY
SIPYIWGATAIGVNGDAVDPKSVTSWADLWKPEYKGSLLLTDDAREVFQM
ALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPANPYMEGEVNL
GMIWNGSAFVARQAGTPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLI
NFLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLYPDAETIKNGE
WQNDVGAASSIYEEYYQKLKAGR
3D structure
PDB1poy Crystal structure of PotD, the primary receptor of the polyamine transport system in Escherichia coli.
Chain3
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SPD 3 W34 E36 Y37 S83 Y85 D168 E171 W229 W255 D257 Q327 W9 E11 Y12 S58 Y60 D143 E146 W204 W230 D232 Q302 MOAD: Kd=3.2uM
Gene Ontology
Molecular Function
GO:0019808 polyamine binding
GO:0019809 spermidine binding
GO:0019810 putrescine binding
Biological Process
GO:0015846 polyamine transport
GO:0015847 putrescine transport
GO:0015848 spermidine transport
GO:1903711 spermidine transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

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External links
PDB RCSB:1poy, PDBe:1poy, PDBj:1poy
PDBsum1poy
PubMed8621624
UniProtP0AFK9|POTD_ECOLI Spermidine/putrescine-binding periplasmic protein (Gene Name=potD)

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