Structure of PDB 8vty Chain 2y

Receptor sequence
>8vty2y (length=96) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKEPQGFVADA
TINTPNGVLVASGKHEDMYTAINELINKLERQLNKLQHKGEARRAA
3D structure
PDB8vty Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2y
Resolution2.6 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2y N4 I5 T6 S7 K8 Q9 R17 K29 W30 Q31 H33 I35 Q46 T53 N55 V62 A63 T72 K80 R83 Q84 N86 K87 H90 K91 E93 A94 R95 R96 N2 I3 T4 S5 K6 Q7 R15 K27 W28 Q29 H31 I33 Q44 T51 N53 V60 A61 T70 K78 R81 Q82 N84 K85 H88 K89 E91 A92 R93 R94
External links
PDB RCSB:8vty, PDBe:8vty, PDBj:8vty
PDBsum8vty
PubMed39039256
UniProtP0AD49|YFIA_ECOLI Ribosome-associated inhibitor A (Gene Name=raiA)

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