Structure of PDB 8vtx Chain 2r

Receptor sequence
>8vtx2r (length=68) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
AKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKT
IKRARILGLLPFTEKLVR
3D structure
PDB8vtx Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2r
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2r K49 I50 R53 A60 K61 R64 K68 K71 R72 R74 I75 F81 K30 I31 R34 A41 K42 R45 K49 K52 R53 R55 I56 F62
BS02 MG 2r R32 D33 R13 D14
External links
PDB RCSB:8vtx, PDBe:8vtx, PDBj:8vtx
PDBsum8vtx
PubMed39039256
UniProtQ5SLQ0|RS18_THET8 Small ribosomal subunit protein bS18 (Gene Name=rpsR)

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