Structure of PDB 8ev7 Chain 2r

Receptor sequence

>8ev72r (length=68) Species: 300852 (Thermus thermophilus HB8)

AKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKT
IKRARILGLLPFTEKLVR

3D structure

• PDB: 8ev7 Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome.
• Chain: 2r
• Resolution: 2.89 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	2r	K49 I50 R53 K61 R64 A67 K68 K71 R72 R74 I75 F81	K30 I31 R34 K42 R45 A48 K49 K52 R53 R55 I56 F62

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0070181 small ribosomal subunit rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8ev7, PDBe:8ev7, PDBj:8ev7
• PDBsum: 8ev7
• PubMed: 37537169
• UniProt: Q5SLQ0|RS18_THET8 Small ribosomal subunit protein bS18 (Gene Name=rpsR)