Structure of PDB 8vtv Chain 2p

Receptor sequence
>8vtv2p (length=82) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLK
VDVERARYWLSVGAQPTDTARRLLRQAGVFRQ
3D structure
PDB8vtv Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2p
Resolution2.55 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 2p M1 K3 R5 L6 R8 G10 K12 H13 H16 Y17 R18 D23 R25 R26 K27 R28 G30 K31 P41 K43 T44 W59 V62 G63 T67 D68 T69 R72 R75 F80 M1 K3 R5 L6 R8 G10 K12 H13 H16 Y17 R18 D23 R25 R26 K27 R28 G30 K31 P41 K43 T44 W59 V62 G63 T67 D68 T69 R72 R75 F80
External links
PDB RCSB:8vtv, PDBe:8vtv, PDBj:8vtv
PDBsum8vtv
PubMed39039256
UniProtQ5SJH3|RS16_THET8 Small ribosomal subunit protein bS16 (Gene Name=rpsP)

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