Structure of PDB 8uvs Chain 2o

Receptor sequence
>8uvs2o (length=88) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHH
SHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG
3D structure
PDB8uvs Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Chain2o
Resolution2.75 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2o H53 L56 V60 G89 H52 L55 V59 G88
BS02 rna 2o P2 K8 F18 T22 G23 S24 Q28 L31 R35 L39 H42 H46 D49 H51 S52 R54 G55 M58 M59 G61 R65 R68 Y69 P1 K7 F17 T21 G22 S23 Q27 L30 R34 L38 H41 H45 D48 H50 S51 R53 G54 M57 M58 G60 R64 R67 Y68
External links
PDB RCSB:8uvs, PDBe:8uvs, PDBj:8uvs
PDBsum8uvs
PubMed38165935
UniProtQ5SJ76|RS15_THET8 Small ribosomal subunit protein uS15 (Gene Name=rpsO)

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