Structure of PDB 8vty Chain 2n

Receptor sequence
>8vty2n (length=60) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKG
QLPGVRKASW
3D structure
PDB8vty Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2n
Resolution2.6 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2n A2 R3 K4 A5 L6 E8 K9 R12 K15 F16 K17 V18 R19 Y21 R23 C27 R29 R31 S32 V33 Y34 R35 I42 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K8 R11 K14 F15 K16 V17 R18 Y20 R22 C26 R28 R30 S31 V32 Y33 R34 I41 R44 E45 K57 S59 W60
BS02 ZN 2n C24 C27 C40 C43 C23 C26 C39 C42
External links
PDB RCSB:8vty, PDBe:8vty, PDBj:8vty
PDBsum8vty
PubMed39039256
UniProtP0DOY6|RS14Z_THET8 Small ribosomal subunit protein uS14 (Gene Name=rpsZ)

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