Structure of PDB 8vty Chain 2j

Receptor sequence
>8vty2j (length=96) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
RIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPF
KHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT
3D structure
PDB8vty Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2j
Resolution2.6 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 2j K7 R9 H13 G36 P37 I38 P39 L40 P41 R43 V44 R45 T48 R51 G52 P53 F54 H56 K57 R60 H62 L71 K3 R5 H9 G32 P33 I34 P35 L36 P37 R39 V40 R41 T44 R47 G48 P49 F50 H52 K53 R56 H58 L67
BS02 MG 2j I74 T100 I70 T96
External links
PDB RCSB:8vty, PDBe:8vty, PDBj:8vty
PDBsum8vty
PubMed39039256
UniProtQ5SHN7|RS10_THET8 Small ribosomal subunit protein uS10 (Gene Name=rpsJ)

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