Structure of PDB 6xqd Chain 2j

Receptor sequence
>6xqd2j (length=96) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
RIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPF
KHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT
3D structure
PDB6xqd Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Chain2j
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 2j K7 R9 H13 S35 G36 P37 I38 P39 L40 P41 T42 V44 R45 T48 R51 G52 P53 F54 K55 H56 K57 R60 H62 H68 R70 L71 K3 R5 H9 S31 G32 P33 I34 P35 L36 P37 T38 V40 R41 T44 R47 G48 P49 F50 K51 H52 K53 R56 H58 H64 R66 L67
BS02 MG 2j I98 K99 I94 K95
BS03 MG 2j R5 I74 R1 I70
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6xqd, PDBe:6xqd, PDBj:6xqd
PDBsum6xqd
PubMed32817463
UniProtQ5SHN7|RS10_THET8 Small ribosomal subunit protein uS10 (Gene Name=rpsJ)

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