Structure of PDB 8vtu Chain 2h

Receptor sequence
>8vtu2h (length=137) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
LTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERV
DVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIP
RVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW
3D structure
PDB8vtu Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2h
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2h T3 A7 D8 T11 R12 R14 N15 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V97 R105 S113 T114 S115 G128 G130 E132 T2 A6 D7 T10 R11 R13 N14 K20 S28 R29 F30 K55 R74 K87 P88 G89 R90 R91 Y93 V96 R104 S112 T113 S114 G127 G129 E131
External links
PDB RCSB:8vtu, PDBe:8vtu, PDBj:8vtu
PDBsum8vtu
PubMed39039256
UniProtP0DOY9|RS8_THET8 Small ribosomal subunit protein uS8 (Gene Name=rpsH)

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