Structure of PDB 8uvs Chain 2h

Receptor sequence
>8uvs2h (length=137) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
LTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERV
DVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIP
RVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW
3D structure
PDB8uvs Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Chain2h
Resolution2.75 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 2h T3 D4 P5 T11 R12 R14 N15 S29 F31 R75 K88 P89 G90 R91 R92 Y94 G96 V97 R105 S113 T114 S115 G130 E132 T2 D3 P4 T10 R11 R13 N14 S28 F30 R74 K87 P88 G89 R90 R91 Y93 G95 V96 R104 S112 T113 S114 G129 E131
External links
PDB RCSB:8uvs, PDBe:8uvs, PDBj:8uvs
PDBsum8uvs
PubMed38165935
UniProtP0DOY9|RS8_THET8 Small ribosomal subunit protein uS8 (Gene Name=rpsH)

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