Structure of PDB 6xqe Chain 2g

Receptor sequence
>6xqe2g (length=155) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQ
EKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLAL
RWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAY
AHYRW
3D structure
PDB6xqe Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Chain2g
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2g A2 R3 R4 R6 A7 R10 N28 K29 I30 R32 G34 K35 K36 N37 L38 R41 R79 R94 S98 R102 N109 R114 R115 A116 A1 R2 R3 R5 A6 R9 N27 K28 I29 R31 G33 K34 K35 N36 L37 R40 R78 R93 S97 R101 N108 R113 R114 A115
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6xqe, PDBe:6xqe, PDBj:6xqe
PDBsum6xqe
PubMed32817463
UniProtP17291|RS7_THET8 Small ribosomal subunit protein uS7 (Gene Name=rpsG)

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